We brought down 2 cats, by air, no problems, no pills. First, contact the airline about restrictions, the one we used (Allegiant) required one pet per flyer, and one pet per row, and an FAA rated pet carrier. Additional ticket for each pet $75. Amtrak would not allow pets, except service dogs, and the movers would not take pets because of the duration of the moved 2-3 days.
As for the lanai, we bought portable pet fencing for PETCO (I think) and attached it inside the lanai aluminum structure to make sure the kitties could not get out.
Hope this helps.
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Pennsylvania, for 60+ years, most recently, Allentown, now TV. 
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