Depends
Are you seasonal or year round? Do you plan to add ac/heat? What is the lanai's orientation when you will be using it most? We left ours screened for 4 years, love it like that when it was nice weather spring and fall, but just couldn't use it a lot in cold months some years. Finally added full-length triple-track windows, exposes about 65% of screen when open all the way, but warms up just fine on sunny cold days. I looked at vinyl, acrylic and glass. Small CYV lanai.
One contractor suggested double-pane, but the one we went with (Custom Windows & Doors) said we didn't need it. We are very happy with the look and the usability.
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