What is your family history? Did your father have an elevated cholesterol and live to 85 with no cardiac issue? Don't treat numbers in isolation. If you have a high HDL that is "protective" against the influence of a high LDL. None of this is clear cut and the understanding is evolving. Recently the recommended healthy lipid level was lowered.
From Mayo
For predicting your risk of heart disease, many doctors now believe that determining your non-HDL cholesterol level may be more useful than calculating your cholesterol ratio. (that is the total cholesterol/HDL) And either option appears to be a better risk predictor than your total cholesterol level or even your low-density lipoprotein (LDL, or "bad") cholesterol level.
To calculate your cholesterol ratio, divide your high-density lipoprotein (HDL, or "good") cholesterol number into your total cholesterol number. An optimal ratio is less than 3.5-to-1. A higher ratio means a higher risk of heart disease.
Non-HDL cholesterol, as its name implies, simply subtracts your HDL cholesterol number from your total cholesterol number. So it contains all the "bad" types of cholesterol.
An optimal level of non-HDL cholesterol is less than 130 milligrams per deciliter. Higher numbers mean a higher risk of heart disease.
Here is an interesting read which may not answer your question
http://www.scientificamerican.com/ar...rol-conundrum/
There are two studies mentioned pending, one on niacin, results are here:
http://www.prnewswire.com/news-relea...196686811.html
and one on zetia with a statin
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712882/
As you will see while both niacin and zetia with statin produced better lab values they were both useless in improving patient outcome.