We also use ortho home defense and don't have pets. We did one initial treatment inside a year ago when we first started and now we only do the perimeter every 3 months. We have had no pests in the house at all. He will occasionally treat the inside of the garage also. Ortho is supposed to be safe for humans to use inside but there are specific instructions on the bottle about how to do this including vacating the house for a specific amount of time and letting the treatment dry before allowing children or pets back inside.
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