I have been on it successfully for 2 years without any problems. This has been a great relief fo my osteoarthritis, allowing me to stay active playing golf and using the gym. OTOH, My wife tried for a short period of time and it caused her a bit of stomach distress. Her MD prescribed something else. If you get an adverse reaction you should ask your MD for something else. I don't see the side effects as anything worse than Advil of Aleve.
Best
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