Polar Bear - I want to commend you and your wife for taking this approach to helping elderly parents live out their lives in a safe and comfortable environment.
In the past I have seen homes with inlaw suites for sale, mostly in the older neighborhoods and especially The Hammock area of Spanish Springs where the homes are very big. I would think a good realtor would be of assistance in this case. If you could find a home where your inlaws could walk to a square on their own, that would be perfect. I know from experience that you will need to get a break from one another from time to time. This link is to a home with inlaw suite which was sold recently in Tierra Del Sol so they are available.
306 Carrera Dr, The Villages, FL 32159 - realtor.com(R)
I hope you find what you need for both parties!