I like 80 degrees day and night while we are gone. After several months, there are no issues or smells. This only costs about $50 per month in electricity.
Part of running the A/C is that not only does it de-humidify the home but the air movement keeps out-of-the-way places like closets from developing mold.
I have a wifi based weather system with one temperature sensor in the kitchen. While we are gone, at 80 degrees, it shows temperature drops from the A/C turning on about every 4-6 hours during the day (with 0-1 during the night). This strikes me as a good number of 'air exchanges' while we are gone. Plus the humidity is good.
In non-summer months, keeping your A/C at 85 or 90 may result in the A/C not turning on for an entire day. That would be bad.
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