Vinegar may work. If that doesn't work then try affresh. It is a Gigantic Tablet that you can use in a Washing Machine, Coffee Maker or a Dishwasher. I would also be sure that there is no big piece of something around the drain before you go thru the treatment process. Also, be sure the dishwasher is draining fully. We run these Tablets thru each appliance on the First of the Month without fail. Good Luck. If all these things don't work I'm afraid you will have to sell the house.