I've responded to these threads before. I don't know how many folks have taken my suggestion, but believe me, it is at least 30 minutes faster than any other route from I-95 North. We live on Nancy Lopez so this will work for you too...
I-95 thru Jacksonville to St. Augustine. Rt. 207 west till it ends in Palatka; right on Rt 17 North for about 1/4 mile then left on Rt 100 West through town to Rt 19 South. 19 to Salt Springs; right on Rt 314 West to Rt 35; left on Rt 35 to 441/27 to Rt. 42 and TV.
Going through Palatka is never a problem. The Rt. 35 stretch can be slow during the day so you might consider staying on Rt 19 past Salt Springs to Altoona, then right on Rt 42 all the way to TV. Happy Motoring!
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