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Old 04-02-2020, 10:50 AM
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blueash blueash is offline
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Default This one shows benefit, from Wuhan China

And today a new study. This out of China so some of you don't believe anything out of China can ignore this one, unless of course it fits your preconceived ideas.

Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial | medRxiv

This study was randomized with a control group. It has not been peer reviewed. It was done on patients with mild disease, not severe disease.

Quote:
But for Time to clinical recovery, the body temperature recovery time and the cough remission time were significantly shortened in the HCQ treatment group. Besides, a larger proportion of patients with improved pneumonia in the HCQ treatment group (80.6%, 25 of 32) compared with the control group (54.8%, 17 of 32). Notably, all 4 patients progressed to severe illness that occurred in the control group. However, there were 2 patients with mild adverse reactions in the HCQ treatment group
All the patients received what the article calls standard therapy

Quote:
all received the standard treatment (oxygen therapy, antiviral agents, antibacterial agents, and immunoglobulin, with or without corticosteroids), patients in the HCQ treatment group received additional oral HCQ (hydroxychloroquine sulfate tablets, Shanghai Pharma) 400 mg/d (200 mg/bid) between days 1 and 5
So this is not a study of HCQ, rather it is a study of HCQ given with antivirals, antibacterials, immunoglobin, and sometimes steroids. Keep the findings clear in your mind that therefore this study does not show that HCQ by itself benefits. Only that HCQ when added to all those other interventions shows benefit.

Also note that the only statistically significant benefit was in time to decrease fever and cough. The difference in chest findings tended to favor HCQ but was not statistically significant.

As to the personal attacks at me for actually posting the studies and their findings. I have posted every single one I have found, both those that show benefit and those that failed. It is about 50/50 at this time. It you already have your mind made up you have my permission to stop reading my posts about the studies. I don't have my mind made up because the data is not clear and the science is not established. Some people have open and inquisitive minds and are amenable to change based on evidence. Some people don't.
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