I am not saying that HCQ with or without other therapeutics is of benefit or not. I am just reporting every study I can find.
This is from France. They looked back at the records from 4 hospitals of all patients who were ill enough to be admitted and required oxygen help, but not ICU ill at the time of admission. Then they analyzed the hospital course comparing those who did vs did not get HCQ. The patients were not randomized but the authors used the records to check whether the treated vs the untreated patients differed on admission in several ways.
Interestingly "All comorbidities were less frequent in the HCQ group." This would mean that the likelihood of progressing to severe illness would theoretically be higher in the NOT treated group as they had more comorbidities. The differences were trends, not significantly different.
84 patients received HCQ, 97 did not receive HCQ.
Quote:
20.5% patients in the HCQ group were transferred to the ICU or died within 7 days, compared with 22.1% in the no-HCQ group
For the secondary outcomes,
2.8% of patients in the HCQ group died within 7 days,
compared with 4.6% in the no-HCQ group
Similarly, 27.7% of the HCQ group and
24.1% of the no-HCQ group developed ARDS within 7 days
|
None of these are significant differences. See the article for full statistical analysis.
This study showed no benefit on any of the measures examined. This is limited to patients admitted with an oxygen requirement but not ICU ill on admission.
You can read the details
HERE. Note this is pre-publication and not yet peer reviewed.