Talk of The Villages Florida - View Single Post - Coronavirus ability to mutate vastly underestimated, some strains more deadly
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Old 04-22-2020, 10:38 AM
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blueash blueash is offline
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I read, but didn't really understand, the whole paper. They did genetic sequencing on the viral samples from 11 patients all hospitalized in a single hospital. All but one were directly connected to early cases from Wuhan but in a city several hundred miles away.

None of the 11 had identical genomes. Every single strain differed if I'm reading the paper correctly. They did not comment on whether variations that had produced higher viral replication in their cell tissue model were from those who were clinically sicker.

None of these strains were subclinical in these patients, all were hospitalized. This is going to be very complex. In producing a vaccine it will have to target a stable protein on the virus, or have components targeting several variations of those proteins, as is done with influenza. This is potentially bad news in the hope for an early vaccine.