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Originally Posted by chet2020
There are trials called "challenge trials" where they give people the experimental vaccine, then give them the live virus. These trials are considered unethical by many. However, they are highly efficient and fast. There is a group in England that wants to run challenge trials and the last time I looked, they had 37,000 people that would volunteer for such trials.
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My understanding is that the participants in this type of "challenge trial" is that they receive a low inoculation of the virus. Hopefully, the participants do not have bad outcomes if they do contract the virus, having either mild symptoms or are asymptomatic.