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Old 11-21-2020, 05:44 AM
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coffeebean coffeebean is offline
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Default How is vaccine efficacy determined?

I have one question as to how the Covid vaccine efficacy is determined. From what I understand, people who participate in the vaccine trials are either vaccinated with the actual vaccine or are vaccinated with a placebo. Then, all of people who participate in the trial go out into the community to "live their lives normally".

Now the question.......are those people in the trial wearing masks and social distancing or are these people in the trials not wearing masks and social distancing? Even if the trial people do NOT follow guidelines, people around them in the community may be following guidelines and wearing masks and social distancing.

I hope you are following my train of thoughts here. Bottom line......just how is the efficacy of a vaccine determined if masking and social distancing are being practiced by those involved in the trial and by the community they are exposed to?
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Last edited by coffeebean; 11-21-2020 at 03:20 PM.