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Thread: How is vaccine efficacy determined?
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Old 11-22-2020, 11:58 AM
Altavia Altavia is offline
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Originally Posted by biker1 View Post
Regarding the Pfizer/BioNTech vaccine, the cold storage requirements for shipping and end use are apparently not as extreme as longer term storage. Reference was made to this on a recent press conference at the White House. It appears that Pfizer/BioNTech have shipping containers that use dry ice and the vaccine can be maintained for a week or more with dry ice. Also, once thawed, the vaccine is apparently usable for up to 5 days. Needless to say, the essentially "just in time delivery" nature of this vaccine complicates the logistics but it doesn't sound as if new refrigeration equipment will be needed at every end use location.
It is also likely Pfizer is stability testing in parallel various conditions that may ease the requirements. Launch what they know is stable first.

Moderna has been testing RNA vaccines longer so likely have more long term experience/data.
Last edited by Altavia; 11-22-2020 at 07:51 PM.