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Originally Posted by biker1
You can't use the flu to draw conclusions about the efficacy of the coronavirus vaccines or the impact of mutations on it's efficacy.The mutation characteristics are different between the flu and the coronavirus. Some viruses, such as measles, are pretty stable where it matters so the vaccine continues to work. The developers are expecting the vaccines to be viable for a longer period of time then the flu vaccines. How long? We will see. There is a lot of information available about the Pfizer/BioNTech and the Moderna vaccines.
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Not entirely, but it's all we have in general. COVID-19 has mutation characteristics closer to H3N2 influenza than H1N1 strains. But this vaccine is so different from traditional "flu shots" that we are in uncharted territory. Early studies based on 42,000 test subjects showed a 95% efficacy (162 in the placebo group contracted COVID, 9 severe as opposed to 8 in the treatment group, 1 severe)