The differences are small. Certainly not enough to worry about. The probability differences between being vaccinated and not being vaccinated is much greater than the differences in vaccines, either with one or two doses of Pfizer or Moderna compared with J&J.
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Originally Posted by coffeebean
The Moderna and Pfizer vaccines have a higher efficacy (80%) after their first shot than the "one and done" J&J vaccine. You can consider the mRNA vaccines as "one and done" if you only get one shot and still have a better efficacy than J&J.
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