Quote:
Originally Posted by ThirdOfFive
It is something I've been asking myself as well.
In the case of Invermectin, as I understand it, it is a drug that has been around for decades, mainly as an anti-parasitic. No more or less dangerous than any other drug. However the CDC has not approved the use of Invermectin for COVID treatment--their reason? That it has not been adequately tested in clinical trials!
This, from the same organization that gave the OK for the Moderna, Pfizer, and J&J vaccines, none of which had had anything close (by their own standards) to "adequate clinical trials".
You have to wonder about this.
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As far as the safety of Ivermectin goes, it has got to be the safest, most widely prescribed drug in existence. 4 billion + doses administered since the mid 70s, 44 deaths. Aspirin kills more than that in a year.
As of right now, there have been something like 66 trials of Ivermectin for Covid. I don't know the exact number but it grows every week. Oxford started a trial recently. The vast majority are RCT, a few are double blind, pretty much all of them are positive in reducing symptoms and mortality. There are two I believe that are neutral.
Most are small, it's true. Many of the trials have cofounding issues, and none were done by big pharma. There is a positive signal there, of that there is NO questions. It also seems to cure long covid in about 80% of the cases, but data on that is lacking.
They approved Remdesivir based on one trial where the end point was altered to get a positive outcome. By that metric, Ivermectin should be the standard of care everywhere but there's no money in it. Even Merck came out against it. Of course, they have a competing drug in the pipeline. Show me the incentive, I'll show you the outcome.
There are very few drug interactions with Ivermectin, Warfarin is one, but then, who the heck is still on that one as there are better drugs out now. IVM should not be taken willy nilly, but look at India? They hand it out to peasants who don't seem to have any issue with it. By the way, the precipitous drop in cases in India? Correlates pretty much exactly to when IVM was mass distributed? What does it mean? Again, a strong signal that should not be dismissed.
That said, there are now nasal sprays that seem to be doing the trick for prophylaxes. Expect that to start getting some real air time soon. Of course they will probably be $10 a dose, 3 times a day, but that's something.