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Originally Posted by Brynnie
I reacted the same way to Covid booster #2 (4th Covid shot overall). Fever of 101.5, chills, headache, and body aches for 2days. Felt fatigued, even on the 3rd day.
Not fun.
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Same for me, wanted a boost prior to going on a cruise in a few weeks and had a strong response.
I switched from Pfizer to Moderna for booster 2 based on publications indicating they're may be some advantages doing so.
Pfizer, Moderna vaccines aren’t the same; study finds antibody differences | Ars Technica
"Both vaccines generate strong levels of neutralizing antibodies, which can bind to the virus and prevent it from infecting cells.
But according to the study, the vaccines generated different antibody profiles overall. Specifically, the antibody response to the Pfizer/BioNTech vaccine skewed to a class of antibodies called IgG and IgM, which are often found in the blood. The
Moderna vaccine, meanwhile, generated relatively elevated levels of IgA antibodies, a class of antibodies generally found on mucosal surfaces, such as the respiratory tract—where SARS-CoV-2 infections begin.
Additionally, the Moderna vaccine spurred relatively higher levels of antibodies that activate immune cells called natural killer cells. It also generated higher levels of antibodies that activate immune cells called neutrophils to ingest and kill (phagocytize) invading germs."