[NotGolfer]

I'm so sorry your wife is suffering. I have both of those plus fibromyalgia. We're all different with our diseases so how she responds to treatments may be different than others. You said she's pursued treatments to no avail. I don't know that OTC can help much as the RX meds are supposed to slow down the progression. OTC and pain meds just cover the issues that cause the pain. One thing I found though to help my fibro. is CBD---I use both tincture and gummies at bedtime. I would say she needs to continue with a rheumatologist. IF she's unhappy then find another one. Dr. Gresh in Ocala is a good one. I see Catherine Sullivan at the Specialty Clinic but heard she's not taking new patients. Not sure if that's correct or not. Used to go to Simed but can't recommend anyone there.
Osteoarthritis comes from aging and use of the body parts. It's different than RA, which is an autoimmune disease. I can't take nsaids so my rheumatologist recommended acetametaphin. She also prescribed a muscle relaxant that I take at bedtime. If pain really hits in certain areas, a heating pad or a soak in the tub might help. I've been the route of pain specialists and won't do it again. Steroids just aren't good for your body. They thin the bones, skin tissue and veins...example with me is being poked for labs or having IV's in the hospital. My veins are hard to find now AND I "blow" the IV's so multiple tries have to happen which isn't fun. PLUS if you get the steroid shots from a pain specialist---I'm talking the kind where you have to fast and they use an x-ray machine to place the needle---these are short term fixes.