Given that there are typically hundreds of billions of stars in a galaxy and hundreds of billions of galaxies in the universe, it is almost assured that intelligent "alien" life exists in at least one more place than earth.
That said, we will never know for certain because of the distances involved. It would take thousands of years, perhaps even tens or hundreds of thousands of years to traverse the distances, assuming life could even survive for so long in such a hostile environment as deep space. Furthermore, by the time the "signs" arrived, the sender would likely have long since gone extinct.
Be careful what you wish for. As Stephen Hawking once said (paraphrasing); "alien" life (i.e. European settlers) was not such a good thing for our Native Americans".
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