Quote:
Originally Posted by blueash
None of the patients were diagnosed with myocarditis. All had a very transient rise in troponin. This is not my field, you may be better equipment to analyze their data. The pre-print article is HERE https://onlinelibrary.wiley.com/doi/...1002/ejhf.2978
The authors tested using high-sensitivity cardiac troponin which has a lower range of normal in females because of their lower cardiac mass. There were 777 persons, 40 of whom showed an increase above "the upper limit of normal" adjusted by sex. "sex-specific 99th-perentile of healthy individuals and upper-limit of normal (ULN) 8.9 ng/L in women and 15.5 ng/L in men,"
In 18 of the 40 they felt other reasons explained the increase [the authors do not say what the other reasons were]. Of the remaining 22 persons, 20 were female and only 2 were male. The median value of those with elevations on day 3 was 13.5 and on day 4 when the test was repeated the median value of those 22 patients was 6.0
All 22 had repeat troponin testing, EKG, and the authors clearly wrote that none were diagnosed with myocarditis, they instead use the term vaccine associated myocardial injury.
Re your comment about exercise, see Just a moment...
where healthy bicycle racers had high sensitivity troponin measurement before, 3 hours after and 24 hours after a race. The median before the race was 1.9 and three hours after was 60, a level none of the vaccine patients reached. 24 hours after the race the troponin level was still over the 99th percentile in about 1/3 of the racers. |
Thanks---I read through the study and personally found it to be garbage.
They only had 740 participants, of which only 22 had a miniscule rise in Troponin. All markers of systemic inflammation fell outside of a P value of <0.05. Symptoms reported were basically all somatic and were actually less in the 22 patients with the small troponin rise. I have trouble agreeing with the terminology of "myocardial injury" to describe the pathophysiology they were studying. Maybe these 22 patients hiccupped more than the rest.