I've tried a number of different ways and found the best to be most of what's said above about 301, but I veer off in Waldo on Rte 24. It runs into Gainesville, and then I get I-75 south down to TV. I like it as it gets me off 301 a lot sooner - and yes there are speed traps there. I saw one in Waldo just after the turn onto 24.
This will put you on I-75 at exit 383 and to get to TV north end you get off at 341 (42 miles at 7o mph speed limit) or for the south end exit 329 (Wildwood).
We usually make a reservation in Florence SC on the way down and Rocky Mount NC on the way back. I do reservations even though I probably don't need them but I got stuck once in the motel from hell!
Enjoy the trip!
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