The better Route would be Take 10 to 20 east, Take I-20 over to Jackson Miss and Take Hwy 49 south from Jackson to Hattiesburg,, Then get on I-59 South for a few miles only, Then Take Hwy 98 Down to Mobile, Alabama... That will bring you to I-65 right there in Mobile. Take 65 south about 6 miles and it dead ends into I-10. Head east on 10,, Pick up 75 south.....
That is the best and fastest route. That is how we did it over the road truckin style. I always tell people to go that way. Look at it on the map. Very easy route. Most of the road from Jackson Miss to Mobile is 4 lane highways....
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