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Old 07-07-2010, 10:53 PM
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Smile Osteoporosis

The class of drugs called bisphosphanates includes Fosamax (alendronate), Actonel (risedronate), and reclast (zoledronic acid). They work by inhibiting bone resorption. In the pharmacy, we dispense much more generic fosamax than any of the others. This is probably because it is on the Wal-Mart $4 list. (disclosure....I still work part time as a Wal-Mart pharmacist). Fosamax 70mg is taken once a week. Actonel is usually taken once a month but has different dosing schedules for some people according to their conditions. I have seen one study that says people can be switched from once weekly fosomax to reclast without any problems.
A few things to remember when taking these drugs. They can be damaging to the esophagus if not taken correctly.
1. they should be taken immediately after getting out of bed in the morning before eating or drinking anything.
2. they should be swallowed whole with a glass of water
3. you should remain standing, sitting or walking for 30 to 45 minutes after taking it
4. you should not eat or drink anything but water for 30 to 45 minutes.
So, due to price I would recommend generic fosamax.
Disclaimer: Please consult your doctor or pharmacist concerning side effects, adverse reactions, or drug interactions.