We have driven I57 - I24 - I75 several times. We were always leaving from Central Illinois, so I74 to I57 in Champaign. We've always had good luck with this route.
When you get to Atlanta, be sure to use the HOV lane and you will zip right through. I've been through Atlanta on Friday @ rush hour and the HOV lane is moving good. I believe it's a great drive, right through the heart of Atlanta. Amazing sight at night.
Have a nice drive....
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