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IMHO one's decline is a progression of self-abuse over many years. I have seen this many times by observing the health habits of friends and most recently my gentleman friend of 20-years (R.I.P.) through the addictions of cigarettes, alcohol, and the wrong food.
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Sorry for your loss, ConeyIsBabe. I can relate to what you have said as I have a habit of observing lifestyles too and I usually can see how lifestyle is connected to health status and longevity.
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I have inherited some crappy genes ~ low intelligence, alzheimers, parkinsons, diabetes, etc. As a result, I'm trying my very best to live the most healthy lifestyle within my control to overrule those bad genes. So far, it's working ~ at age 73 I don't need any prescription drugs and I feel great 
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It's pretty much the same for me except you can take out the Parkinsons and insert cancer (lots of cancer and dementia). I also try my best to overrule the bad genes and its working for me too. I'm 70 and don't take any prescription drugs. I don't think it's just a coincidence; living a healthy lifestyle really works!
There was an article in the Daily Sun about a couple living in TV who were both in their late 90s and both of them were drug free. That was a few years ago; I think it was their 75th wedding anniversary. Was that just a big coincidence that they both lived to their late 90s and both were drug free? I don't think so.
I once read (in a book about genes) that genes by themselves can't do anything, they have to be turned on. Take flower seeds: They represent genes to make a flower. But what happens if you buy a package of flower seeds and leave them in the package? Nothing happens. You have to plant them in fertile soil and keep them watered. In another book, "The Biology of Belief", Dr. Bruce Lipton made the case that "genes are not our destiny." The evidence of this is everywhere, people just need find what it takes (a better lifestyle) and put it into practice.