We did the Amsterdam to Basel, Switzerland with Uniworld last year. Incredible! We picked Uniworld after some research. Friends took Viking and Vantage, and recommended both. We decided on Uniworld for two reasons. It was top rated by Conde Nast, and the ship was brand new in March (SS Antoinette). The highest rated on Conde Nast was Grand Circle. Overall, I think the River cruises are wonderful and whoever you go with you will probably recommend afterward. I suspect most people only get to choose once, if you go again, you'll go with the same line.
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