[lovsthosebigdogs]

I am sorry to hear that you are having so many problems with your senior. We had a dog that was around 60 lbs that lived to be 17 that suffered from CGD, Caninne Cognitive Disorder, for many years and used to get very confused. We also had to find ways to accomodate his issues. We used to try to give him things to do while we were gone. Since he didn't see well we used his nose, which still worked. We put a tiny dad of peanut butter in a natural bone and left it where he could locate it. We had a toy that dropped tiny pieces of his regular dog food so we didn't have to introduce new food into his diet with treats- it was an oval, space saucer looking thing that you screwed together wtih dog food or treats inside and when he moved it a piece would fall out. We never made an issue of coming or going. Everything around our departure was VERY relaxed. We never said hello or goodbye to him. It eased him while I went to work and we kept him going til he was 17 and the end was more obvious to us. That's a long life for a dog his size.
Good luck to you. I hope it works with his anxiety. If it's medical, maybe your vet can help. And I have also used Rescue Remedy but i didn't do much for my dog. It is worth a shot; it's not expensive.