Les,
Well you can very easily in fact with minimal exercise.
The hard part is will power.
A vegan or even vegetarian diet will do the weight part.
The elimination of oil yes oil (any & all types) will eliminate all soft plaque in the arteries.
But I believe I posted to you before about that.
rent or buy a copy of "Forks over Knives" if the basics of that dvd are followed it can change your heath dramatically, you will lose the weight you wish to, your arteries will open up in a few months not years.
Drop BP if high cut down on the drugs you may be taking with all their wonderful side effects.