I've done 301 and I've done I-10 to I-75. 301 is shorter by about 50 miles and it's quicker. You just have to pay attention to the speed limit changes which are all well marked. Before we hit Ocala we cut over Rt. 326 to I-75 which we take to the Rt. 44 exit near Wildwood. If you easily become distracted and miss the speed limit changes you're probably better off staying on the interstates but your trip will be a little longer.
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New York State, Alabama, South Carolina, Texas, Italy.
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