Genetic DNA Testing

[Villager Joyce]

I'm thinking about doing it. Have you? What did you think? Did it change your life?

[Xcuse]

I'm thinking about doing it. Have you? What did you think? Did it change your life?

The Mrs & I were curious about unknown ancestry so we went with Ancestry.com DNA testing. The results were surprising in that there were no surprises. Our ancestry turned out to be pretty much what we already knew. We still feel it was worth it just to know for sure.

[graciegirl]

I'm thinking about doing it. Have you? What did you think? Did it change your life?

I would love to do it but it seems like a frivolous waste of a hundred bucks to tight me.

[manaboutown]

The Mrs & I were curious about unknown ancestry so we went with Ancestry.com DNA testing. The results were surprising in that there were no surprises. Our ancestry turned out to be pretty much what we already knew. We still feel it was worth it just to know for sure.

Like you, it verified what I already knew and not with any real degree of precision. Still...it was a start.

[manaboutown]

I would love to do it but it seems like a frivolous waste of a hundred bucks to tight me.

It only costs about as much as a single bottle of good Bordeaux at Costco! https://www.wine-searcher.com/find/palmer+margaux+medoc+bordeaux+france

Just kidding but Costco has quite a nice wine selection!

[villagetinker]

I was curious if the DNA results were stored, and if the results could be accessed by 'others', so I asked "23 and me". I was interested in this service as it recently received FDA approval for medical screening info from DNA. They told me the results were 'destroyed' 2 weeks, if I remember correctly, after the results were mailed out. IMHO, I would contact whatever vendor you are thinking of using and asking what if any information is stored, where, how, for how long, etc.

[graciegirl]

I was curious if the DNA results were stored, and if the results could be accessed by 'others', so I asked "23 and me". I was interested in this service as it recently received FDA approval for medical screening info from DNA. They told me the results were 'destroyed' 2 weeks, if I remember correctly, after the results were mailed out. IMHO, I would contact whatever vendor you are thinking of using and asking what if any information is stored, where, how, for how long, etc.

I am one who doesn't worry about this kind of information being public knowledge. We have participated in many genetic screenings as a family to aid research into Williams Syndrome.

[Wiotte]

I was curious ( you never know, people lie ) so I tested with 23&me. The results were what I expected with one exception. 1/5 of 1 percent Native American. So, since I've traced my ancestors back to 1100 England I thought everyone was accounted for. Somewhere along my line, someone lied. [emoji6]


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[Schneil]

There is a wonderful Genetic genealogy group in The Villages, they would be happy to answer questions about the various DNA tests, as well as ongoing sale promotions
Welcome to The Villages Genealogical Society website! (https://vgsfl.org/)

[rubicon]

For those who have testing I assume the agencies offering DNA testing provide the % of error/accuracy in the testing? would you provide that %?

[carol_baumer]

We tested because our friend came up with unexpecteMy father was half German. I thought I inherited most of that German DNA as as I have some of the streotypical traits (organized, rule-following, neat etc.). Had my DNA tested. Surprise! I only got a very very little Germanic ancestry. Most very expected. Another surprise- 5% West Asian.??!!

[carol_baumer]

Oops- didn't mean to send the above 'reply' yet as was unfinished. Sorry if it looks garbled.

[Villager Joyce]

If my sibling and I were tested, would our genetic results be the same? Presuming I wasn't adopted as my older sister always claimed.

[PennBF]

I had my DNA done and if you just looked at the general area's your history points out then there probably would not be a lot of surprises. Included in the results were a lot of potential 1st, 2nd 3rd, etc cousins and that is where the intelligence comes from. I have a brother who is turning 90 on the 31st of this month and as a present I put together a family history going back to 1510 in England. All the grandfathers, wives, their children and everyone's birth and death dates, along with places of birth. It was a real experience to find out the people of our history, facts, etc. Some of it came from digging into the DNA results, lot from Ancestor.com records, Mormon, etc. It was 2 pages and I also framed copies for other siblings. If your bored and want to add some fun into your spare time try tracing your history. It becomes a little addictive at times. :ho:

[retiredguy123]

For me, this would be a total waste of money to get worthless information.

[Wiotte]

If my sibling and I were tested, would our genetic results be the same? Presuming I wasn't adopted as my older sister always claimed.



You would share 50% of your DNA.


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[Villager Joyce]

You would share 50% of your DNA.


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Is that you -- my older sister who claims I was adopted? I was NOT adopted!

[Boomer]

Is that you -- my older sister who claims I was adopted? I was NOT adopted!


Oh Joyce, please do not worry. Your big sister was just following the rules in "The Big Sister Handbook."

[PennBF]

It is so sad to hear that some think understanding the source of their DNA and the history of their life is "worthless". You wonder what fills their life and if it is some form of desperation or fear or just empty? :ohdear:

[Taltarzac725]

It is so sad to hear that some think understanding the source of their DNA and the history of their life is "worthless". You wonder what fills their life and if it is some form of desperation or fear or just empty? :ohdear:

Relatives on both my father's and mother's sides have done extensive research into our genealogy so I am not sure how much help a DNA test would be. I am pretty sure it would show some Native America and African American DNA as well as my mother's side has ancestors coming over in the 1600s to the colonies. And we now have a whole branch of Jamaican-Americans after late my younger brother married one of these about ten years ago.

[Dan9871]

They told me the results were 'destroyed' 2 weeks, if I remember correctly, after the results were mailed out.

The 23&me website, Our Health + Ancestry DNA Service - 23andMe (https://www.23andme.com/dna-health-ancestry/) , says:

"How large is the 23andMe DNA database?

The 23andMe DNA database has more than two million genotyped customers worldwide. You will continue to find new relatives as our database grows over time."

Also in the user agreement:

"Further, you acknowledge and agree that 23andMe is free to preserve and disclose any and all Personal Information to law enforcement agencies or others if required to do so by law or in the good faith...."

In other parts they say that 23&me retains the rights to genetic data they provide you for research and commercial products.

[thelegges]

I was curious ( you never know, people lie ) so I tested with 23&me. The results were what I expected with one exception. 1/5 of 1 percent Native American. So, since I've traced my ancestors back to 1100 England I thought everyone was accounted for. Somewhere along my line, someone lied. [emoji6]


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Not so lied, as usually left out completely. My great grandmother was 100% native American, great grandfather was Swedish off the boat . First wife came over on boat had two children and died.
My native american great, married had my grandfather and died 4 years later. She is not in any bible, recordings, or pictures. Only third wife is listed. I have pictures of her. If not for my family's in-depth stories of my native American heritage, I would be have never know.

[autumnspring]

Not so lied, as usually left out completely. My great grandmother was 100% native American, great grandfather was Swedish off the boat . First wife came over on boat had two children and died.
My native american great, married had my grandfather and died 4 years later. She is not in any bible, recordings, or pictures. Only third wife is listed. I have pictures of her. If not for my family's in-depth stories of my native American heritage, I would be have never know.

You native american grandmother may not be listed as due to prejudice your family chose to deny her.

RE: 100% native american
That is historically unlikely. History shows that first of all the Indians were crunched together to to the white European invasion. They bred not only with whites but the Indian tribes were one of the few placed that would welcome runaway black slaves.

RE: Family stories
Like any other history, it changes till it is written down and once it is written it may not be true.
I compare what I know about my family with my sister. I know we were in the same family-I HAVE PICTURES TO PROVE THAT but what she knows her view of things is totally different then what I know.

[villages07]

If you are thinking about testing, now is a good time. Ancestry.com sent me an email saying cost is $69 I think for next week or two. The results are pretty basic as far as giving ethnicity and matching you with other subscribers who share your DNA. You can download the raw data and use it on other sites and services for additional research. For $5 promethease.com takes your raw data and compares your abnormal chains to results from published studies that can give you some insight into your good and bad potential for various diseases, medications, conditions, etc. It all gets very scientific and complicated but was interesting to play around with. I also did 23andMe.com. The test is much more expensive but does also delve into health traits. Their raw data was more extensive than ancestry.


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[Carla B]

Someone I know got markedly different results from Ancestry and 23&Me, although both agreed on 100% European ancestry.

[Barefoot]

I'm thinking about doing it. Have you? What did you think? Did it change your life?
My girlfriend was tested by 23 & me.
She was happy that she spent the money and received her results. It didn't change her life.
I haven't been tempted to do the testing.

[rubicon]

Both my paternal and maternal grandparents immigrated from the Campinia region ( villages towns around Naples.
Campinia had Greek origins. As far back as my grandparents ,etc could recall no family member married someone of different nationality

Hence my grandmothers admonishment while she pinched my cheek "you marry a nice Italian girl". :D

[golfing eagles]

My girlfriend was tested by 23 & me.
She was happy that she spent the money and received her results. It didn't change her life.
I haven't been tempted to do the testing.

No need to test, here's your DNA profile:

20% Eskimo
15% Polar bear
10% penguin
20% lobster
15% hockey player
20% BET LOSER!!!! :1rotfl::1rotfl::1rotfl:

[Villager Joyce]

No need to test, here's your DNA profile:

20% Eskimo
15% Polar bear
10% penguin
20% lobster
15% hockey player
20% BET LOSER!!!! :1rotfl::1rotfl::1rotfl:

Seriously. What are your thoughts on the testing, particularly the medical probability/possibility tests?

[Barefoot]

No need to test, here's your DNA profile:
20% Eskimo
15% Polar bear
10% penguin
20% lobster
15% hockey player
20% BET WINNER!

And you are 100% cross threader.
But thanks for your acknowledgement that I won our bet. :evil6:
And now, Village Joyce wants you to be serious and give your medical opinion!

[golfing eagles]

Seriously. What are your thoughts n the testing, particularly the medical probability/possibility tests?

Seriously, you said it yourself-----they are PROBABILITY tests based on DNA sequences that are associated with some diseases. If a disease is a single gene abnormality, the tests are pretty definitive---such as sickle cell or B-thallasemia. But most of the diseases that you and I would be interested in are multifactorial----heart disease, cancers, diabetes, etc. Now the testing becomes less definitive and probabilities take on a bigger role. So common sense needs to prevail-----don't make any final arrangements based on these tests. Then, if you have a higher probability of heart disease, stay fit, maintain ideal weight, and limit fat/cholesterol. If you have a higher probability of lung cancer---DON"T SMOKE!

[golfing eagles]

And you are 100% cross threader.
But thanks for your acknowledgement that I won our bet. :evil6:
And now, Village Joyce wants you to be serious and give your medical opinion!

I realize your prime minister leans a bit left, but that does not give you license to write revisionist history. Very simply, I WON, YOU LOST. However, since I believe it was I that first invented the term "cross-threading", I get more leeway. :1rotfl::1rotfl::1rotfl:

[Villager Joyce]

Seriously, you said it yourself-----they are PROBABILITY tests based on DNA sequences that are associated with some diseases. If a disease is a single gene abnormality, the tests are pretty definitive---such as sickle cell or B-thallasemia. But most of the diseases that you and I would be interested in are multifactorial----heart disease, cancers, diabetes, etc. Now the testing becomes less definitive and probabilities take on a bigger role. So common sense needs to prevail-----don't make any final arrangements based on these tests. Then, if you have a higher probability of heart disease, stay fit, maintain ideal weight, and limit fat/cholesterol. If you have a higher probability of lung cancer---DON"T SMOKE!

You are so smart. Just reading your post made my brain hurt.

[golfing eagles]

You are so smart. Just reading your post made my brain hurt.

That's quite a trick, since there are no pain receptors in the brain!!!!:beer3:

[Villager Joyce]

That's quite a trick, since there are no pain receptors in the brain!!!!:beer3:

Wow. I did not know that. Guess that's why I was a legal assistant and not a brain surgeon.

[dbussone]

Wow. I did not know that. Guess that's why I was a legal assistant and not a brain surgeon.



I did not know GE was a brain surgeon. Maybe he stayed at a Holiday Inn Express. Who knew? [emoji41][emoji106]


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[golfing eagles]

I did not know GE was a brain surgeon. Maybe he stayed at a Holiday Inn Express. Who knew? [emoji41][emoji106]


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Brain surgeon, no. There just weren't enough customers who met the prerequisites. :1rotfl::1rotfl::1rotfl:

But I did stay in a Holiday Inn Express, and paid with the American Express card, before getting on the Orient Express to pick up a package in Paris delivered by Federal Express. I hope I expressed myself clearly!

[Nucky]

We did this thru Ancestry and the results were spot on what we both expected. It also explains why I have no rhythm. :ohdear:

[golfing eagles]

We did this thru Ancestry and the results were spot on what we both expected. It also explains why I have no rhythm. :ohdear:

I haven't done it yet. If you use 23 and me, it also tells you how many Neanderthal genes you have. Probably the reason I haven't done it yet:1rotfl::1rotfl::1rotfl:

[dbussone]

Brain surgeon, no. There just weren't enough customers who met the prerequisites. :1rotfl::1rotfl::1rotfl:



But I did stay in a Holiday Inn Express, and paid with the American Express card, before getting on the Orient Express to pick up a package in Paris delivered by Federal Express. I hope I expressed myself clearly!



You clearly did. 1rotfl::1rotfl::1rotfl:


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[Boudicca]

Ancestry.com put their DNA service on sale occasionally. I had my DNA tested for $75 and DID get surprises. Thought we were German, but Scandinavian instead. Also Iberian and tiny percentage of Irish and British. No surprise with the last two. Maternal G grandmother born in UK of Irish father. I have a degenerative eye disease of the optic nerves which is usually found in middle European Jews. No Jewish connection found thus far. It's a mystery

[SCasey]

The Triplets Put Ancestry Kits to the Test (http://www.thedoctorstv.com/articles/3863-the-triplets-put-ancestry-kits-to-the-test)

[Allegiance]

I'm thinking about doing it. Have you? What did you think? Did it change your life?Extensive Results from DNA tests can be received quickly for an extra $5 or $10 here.

Promethease (https://promethease.com)

[Loudoll]

It was worth it simply to end the suspense as another poster commented. My DNA results were so boring I could hardly get through it. Surprised? Yes, that among my siblings I am the most Irish! Did you know that your siblings get a little different DNA mix than you do? I expected to be heavily German and Jewish or surely French. I am zero Jewish and a speck German. I'm mostly, English. Nothing exciting.

[Loudoll]

No, your results won't be exactly the same.

[thelegges]

You native american grandmother may not be listed as due to prejudice your family chose to deny her.

RE: 100% native american
That is historically unlikely. History shows that first of all the Indians were crunched together to to the white European invasion. They bred not only with whites but the Indian tribes were one of the few placed that would welcome runaway black slaves.

RE: Family stories
Like any other history, it changes till it is written down and once it is written it may not be true.
I compare what I know about my family with my sister. I know we were in the same family-I HAVE PICTURES TO PROVE THAT but what she knows her view of things is totally different then what I know.

We have had DNA tested, by our oldest. He is a physical anthropologist, DNA forensic to 5000 BC. Has dual PHDs Youngest publish by Smithsonian at age 20 and than 23. His specialty is Native Alaskan, Native American, Native Mexico, and Egyptian.

Ours is so extensive he actually bound it in a book. My Native American history was on both sides of my family. Majority of his data comes from actual bones, teeth, hair. In 1800s many people kept those items, not so morbid in those days. My great grandmother, and her sister are buried in a traditional mound, that has to be remounded, every two years. The family stories were more about what she was like, and her life before she died at such a young age. The church has 3 sections in cemetery, has a sign above each entrance, white, black and red. So we are very lucky to know she was 100% native, where she is buried, along with the rest of my family. His research takes years, for a project, and I am pretty sure it would have cost more than $75. We spent a lot of money on that education, but sometimes you get something knowledgeable in return.

I have asked him about the tests on today's market, but he does not have an opinion either way since you do not know how they run their tests.