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-   Current Events and News (https://www.talkofthevillages.com/forums/current-events-news-541/)
-   -   Hydroxychloroquine (https://www.talkofthevillages.com/forums/current-events-news-541/hydroxychloroquine-309557/)

jimjamuser 07-29-2020 01:16 PM
Quote:
Originally Posted by oldtimes (Post 1810269)
The results of any study are greatly influenced by who funds the study
That's why we need to pay MORE taxes, not LESS so that studies are NOT done by private organizations. The taxpayers need to be willing to PAY for good taxpayer sponsored Medical studies. If you choose the cheapest option, you normally get the worst outcomes. A taxpayer MIGHT (?) have more money in their pockets with lower taxes, but, like today you now have to make YOUR life or DEATH decisions on cheap, marginal information. In the 50s through 70s Universities got their research money from government / taxpayers and people GAINED knowledge from GOOD research. Now you have money in your pocket but you are completely UNSURE whether or NOT you can trust your government or your Doctors. Big change from around the 60s when taxes were higher and PROGRSSIVE!!!!

blueash 07-29-2020 01:17 PM
https://www.nejm.org/doi/full/10.105..._railB_article

Just published with three groups. All patients were hospitalized but not severely ill at the time of randomization. One group no medication, one group HCQ, one group HCQ and AZ.

Results in this randomized intervention NO BENEFIT

Also prolonged QT interval changes was only seen in the treated group. So side effects but no benefit. Was this study on the list of 65 global studies. Nope.

mneumann02 07-29-2020 01:26 PM
Thank you. Well stated. Trust science and facts. Not those with agendas.

coffeebean 07-29-2020 01:30 PM
Quote:
Originally Posted by GoodLife (Post 1810036)
DR HARVEY A. RISCH, MD, PHD , PROFESSOR OF EPIDEMIOLOGY, YALE SCHOOL OF PUBLIC HEALTH

“When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective,” Risch explained. “Especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.”

Earlier this month, a large peer-reviewed study found that hydroxychloroquine cut the mortality rate of COVID-19 by more than half and, contrary to previous claims by faulty studies, had no adverse effects on the heart.

Link goes to Newsweek article

You have been blocked
Your link says, "You have been blocked", although the link does work. Thank you for posting this. I would present this article to my doctor in the event my doctor would not prescribe it. I would want my husband to do the same if he needed this medication.

jimjamuser 07-29-2020 01:32 PM
Quote:
Originally Posted by Byte1 (Post 1810325)
I doubt your statement regarding "side effects." They gave the stuff to EVERYONE that was shipped to Vietnam so if your statement is true then thousands of Vets could be suing the gov. for poisoning them. I believe that your "side effects" have been disproved.
Was that the same military organization that gave out agent orange to be inhaled by GIs? That CARING organization?

coffeebean 07-29-2020 01:32 PM
Quote:
Originally Posted by Happinow (Post 1810050)
And if it’s not effective, then why did Chris Cuomo take it? Why are the politicians able to get it? Something stinks here.....
Health care and front line workers are taking this medication too. Problem is, I read that many are taking it as a prophylactic, not once they develop symptoms. I guess they figure if they are asymptomatic for Covid, why not take it?

blueash 07-29-2020 01:36 PM
https://www.nejm.org/doi/full/10.1056/NEJMoa2016638

Another recent study again in the New England Journal looking at using HCQ as a preventative in exposed people, specifically high and moderate risk exposure meaning close contact for greater than 10 minutes to a known positive.

Conclusion
Quote:
Overall, 87.6% of the participants reported a high-risk exposure to a confirmed Covid-19 contact. The incidence of new illness compatible with Covid-19 did not differ significantly between participants receiving hydroxychloroquine and those receiving placebo .... Side effects were more common with hydroxychloroquine than with placebo (40.1% vs. 16.8%), but no serious adverse reactions were reported.
The most recent meta analysis [looking at all published data and combining the results] pre-published on Jul 24 using all data available through Jul 19 concludes:
Quote:
The results of the meta-analysis on comparative studies indicated no significant clinical effectiveness .. for HCQ regimen in the treatment of COVID-19 in comparison to control group ... The same result was observed for the combination of HCQ+azithromycin ... No significant differences were found for both HCQ ..and HCQ+AZM .. mortality rate; however, mortality was affected by age differences according to meta-regression analysis (P<0.000001). No substantial difference was observed for disease exacerbation .. between HCQ group and controls. Also, radiological findings significantly improved in the HCQ group (... Odds of known HCQ adverse effects (diarrhea, vomiting, blurred vision, rash, headache, etc.) occurred in the HCQ regimen group was approximately 3.5 times of control group .., but no substantial differences were found regarding intubation odds between HCQ... Meta-analysis indicated no significant prophylactic effects for HCQ .. Conclusion: This systematic review and meta-analysis showed no clinical benefits regarding HCQ treatment with/without azithromycin for COVID-19 patients. Although mortality rate was not significantly different between cases and controls, frequency of adverse effects was substantially higher in HCQ regimen group.
[my bold]

Now tell me again about how the studies prove that HCQ is beneficial. The final result is not yet in. There are large ongoing randomized studies, but an unbiased look at the conflicting data so far available has overwhelmingly concluded that HCQ benefit is about as likely as that endometriosis is caused by having dreams about sex with demons.

Shamp 07-29-2020 01:42 PM
Can you name a few well respected doctors who agree that this medication is helpful in preventing or treating Covid? I'm not talking about that nut case doc who said she cured 350 patients of covid without wearing a mask. She also said that GYN issues are related to dreaming about sleeping with movie stars and other equally bizarre statements. Believe what you will, but Dr. Fauci likely has more expertise than anyone thinking they know more than their medical doctor.

coffeebean 07-29-2020 01:46 PM
Quote:
Originally Posted by alfredpopcorn@gmail.com (Post 1810124)
Nope - trust your research. They used lancet as basis . They are uninformed physicians- that study was horrible in its set up . And will set lancet back for years as a legitimate publication.
Who are you replying to, the original poster or post #21? Which study are you speaking about?

coffeebean 07-29-2020 01:48 PM
Quote:
Originally Posted by Rwirish (Post 1810129)
Absolutely would not take this. Trust the medical professionals not whacky politicians.
But.......there are countless medical professionals who have seen great results and improved death rates when this drug is used as soon as symptoms appear. That IS trusting the medical professionals.

blueash 07-29-2020 01:52 PM
Quote:
Triciakaye
I think you may be wrong. A study in 2008 by the National Institute of Health said that hydroxy given at early stage of corona virus was beneficial to “some “ Dr Fauci was head of the institute at that time
Quote:
Originally Posted by Bucco (Post 1810407)
2008........Corona Virus.

Don't think that virus existed in 2008, so you are listening to the Fauci personal bashing and truth does not sit well with that group
Corona virus has been known for decades. What did not exist in 2008 was Covid-19 The 19 is a label indicating this particular variety was first noted in 2019.
However Tricia's claim is also wrong. During the SARS epidemic [SARS is also a Corona virus but not the same as Covid-19] the NIH did research looking for anything that might help. It was found in vitro [in a test tube] that HCQ slowed viral growth. It was never tested on humans for that disease. But it was in part because of some NIH research that doctors thought to try HCQ in Covid-19

And the SARS epidemic was not in 2008 but in 2003 mostly.

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

This is the NIH study. Perhaps Dr. Fauci's long experience with using HCQ should add some credence to accepting his fairly authoritative opinion on its utility in Covid-19

coffeebean 07-29-2020 01:59 PM
Quote:
Originally Posted by Lindsyburnsy (Post 1810170)
I would trust Dr Fauci.
Let us remember Dr. Fauci is the expert who told Americans a little white lie early on in this pandemic. He told us that wearing masks were only good for people with Covid and for people who were taking care of patients with Covid. Why did he lie????? Because he was concerned there would not be enough PPE for the front line and health care workers.

Hydroxychloroquine has already been difficult for those patients who take it for autoimmune diseases. I personally know someone who has had difficulty getting the medication that is needed for their illness.

So.......No, I would not trust Dr. Fauci about the efficacy of Hydroxychloroquine. He is guarding the supply for those who are already on the drug for other illnesses than Covid.

coffeebean 07-29-2020 02:08 PM
Quote:
Originally Posted by JudyLife (Post 1810229)
The FDA have not approved this drug for treatment in Covid 19. Your doctor acted responsibly in not prescribing. Hydroxychloroquine has been effective to some extent in treating Lupus and malaria, not Covid 19.
If there is one person who is alive today because they took the Hydroxychloroquine cocktail, it is worth the risk, especially if you do not have a heart condition.

coffeebean 07-29-2020 02:17 PM
Quote:
Originally Posted by TooColdNJ (Post 1810257)
The manager of a large grocery chain is wined and dined by vendors to get them to recommend putting their products on the shelves, and physicians benefit from large pharma in the same, but larger scale way. They’re given vacations, research funding, gifts, etc. by big pharma that spends lots of $$ on marketing. Those long, costly ads onTV is marketing their drugs to the consumers as well. Imagine how many people go to their appointments asking their doctors for those “As seen in TV” drugs, or those endorsed by the President of the United States to treat their health issues. I believe it started with Viagra.

With the onset of COVID-19, I’m sure that the same thing is happening with HCQ— Yale professors and doctors have no scientific proof and are probably cashing in on claims that it could have an effect on the virus— probably for their own personal gains. Especially HCQ— while it might lessen the symptoms or keep us from getting CO19, it would be prescribed if studies proved that it works. Those who have shown milder symptoms are people that could have had milder or no symptoms in the first place.

Dr. Trump’s endorsement, and (unscrupulous) doctors who prescribe the medication, are probably invested in it in some way—even if it’s to benefit from the perks. I highly doubt that it’s being hoarded by politicians and unavailable to us. The possible risks outweigh the (unproven) benefits. If proven to work, don’t you think it would be manufactured to save a lot of lives, or is keeping it from us a new conspiracy theory?

Without solid scientific proof, (even though those now taking it claim to be having problems), there could be long term affects of taking a speculative drug. Maybe it’s worth trying as a last effort for those hospitalized with severe cases, because long-term risks aren’t an issue if someone is on their deathbed. Other than that, I think those doctors who readily prescribe it at this time are being negligent.
The drug is not speculative. This drug has been used for years for many autoimmune diseases. Taking the drug in the end stages of Covid has been shown not to be effective. From what I have read about the Hydroxychloroquine "cocktail" is it should to be taken as soon as symptoms appear to be effective.

coffeebean 07-29-2020 02:21 PM
Quote:
Originally Posted by SusanKD (Post 1810260)
Just a couple of days ago on Television their was some doctors and I think health org Doctors all agree that that medication is NOT going to work to cure Covid. So your doctor is correct.!
My understanding of the effectiveness of the Hydroxychloroquine cocktail is that it is not a cure for Covid. What it does is lessen the length of the disease and also lessens the severity of the disease. It is not to prevent the disease as it must be taken as soon as symptoms appear. This is a problem for aymptomatic people because they would not know when to start the cocktail.


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