The real truth about messenger RNA

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Old 04-09-2021, 05:48 AM
Tmarkwald Tmarkwald is offline
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Default The real truth about messenger RNA

Studies and clinical trials on RNA vaccines for other viruses – and even cancers – have been going on for a decade.

Nobody getting the Moderna or Pfizer vaccine is a test subject of any kind. These are not experimental vaccines in any way. And they do not modify your dna.

Three ways RNA is being used in the next generation of medical treatment

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Old 04-09-2021, 06:40 AM
Swoop Swoop is offline
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Originally Posted by Tmarkwald View Post
Studies and clinical trials on RNA vaccines for other viruses – and even cancers – have been going on for a decade.

Nobody getting the Moderna or Pfizer vaccine is a test subject of any kind. These are not experimental vaccines in any way. And they do not modify your dna.

Three ways RNA is being used in the next generation of medical treatment
This quote come directly from the link you provided:
“The mRNA vaccines that are used to protect against SARS-CoV-2 (the virus that causes COVID-19) are the first of their kind to be licensed for widespread human use.”

Since 2010, most novel vaccines approved by the FDA required about 8 years of clinical development and were based on evidence from a median of 7 clinical trials, including at least 2 pivotal efficacy trials that were randomized, masked, and used a comparator group. Certainly not the case as it pertains the Covid vaccines...
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Old 04-09-2021, 06:51 AM
Tmarkwald Tmarkwald is offline
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Originally Posted by Swoop View Post
This quote come directly from the link you provided:
“The mRNA vaccines that are used to protect against SARS-CoV-2 (the virus that causes COVID-19) are the first of their kind to be licensed for widespread human use.”
Yes, then it goes on to say that studies and clinical trials on RNA vaccines for other viruses – and even cancers – have been going on for a decade. And the key word is 'licensed', since they've passed the checks and trials and determined that the vaccine poses no health risk.

So, you have to either accept or reject the scientists who developed these mRna vaccines. Totally up to you.

I'm simply providing a link to the data. How anyone interprets the data is up to them. The point being made is that this technology and method wasn't created overnight - not by a long shot.
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Old 04-09-2021, 07:11 AM
Tmarkwald Tmarkwald is offline
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Originally Posted by Swoop View Post
Since 2010, most novel vaccines approved by the FDA required about 8 years of clinical development and were based on evidence from a median of 7 clinical trials, including at least 2 pivotal efficacy trials that were randomized, masked, and used a comparator group. Certainly not the case as it pertains the Covid vaccines...


Preclinical work on therapeutic mRNA goes back at least to 1990, 20 years ago...

Want to Know More About mRNA Before Your COVID Jab? | MedPage Today

Never Been Done Before?

While an mRNA vaccine has never been on the market anywhere in the world, mRNA vaccines have been tested in humans before, for at least four infectious diseases: rabies, influenza, cytomegalovirus, and Zika.

mRNA can target tumor-associated antigens expressed mainly by cancerous cells, like certain growth factors. These vaccines have been tested in a range of cancers, including acute myeloid leukemia, multiple myeloma, glioblastoma, melanoma, prostate cancer, and others.

Why Did Earlier Vaccines Stall?

"A major factor is that there's not a sense of urgency," Dennis Burton, PhD, of Scripps Translational Research Clinic in La Jolla, California, told MedPage Today.

Zika has been relatively contained; rabies vaccines are already sufficiently effective; and influenza remains a difficult target, Burton said.

...based on the sheer number of people who will be vaccinated for COVID-19, events will occur, and most will likely be unrelated to the vaccine.

"One of the things we're most concerned about is that people won't get vaccinated," he said. "But the risks of this disease are going to be way higher than the risks associated with vaccination."

Clinical trials for 75,000 people show it’s safe and it’s 95 percent effective,” Dr. Weissman said. “That’s pretty good data to convince people that it is OK.”
While mRNA is a new technology, experts have been working on it for years.

It’s not just as though these technologies were just starting to be developed during the pandemic,” Dr. Moss said. “There has been a lot of preparatory work.”


This is part of The Associated Press’ ongoing effort to fact-check misinformation that is shared widely online, including work with Facebook to identify and reduce the circulation of false stories on the platform.


Pfizer and Moderna did not skip animal trials
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Old 04-09-2021, 08:08 AM
Boffin Boffin is offline
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I thought the focus of this post was the definitive fact that the mRNA used in COVID vaccines does not modify DNA.
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Old 04-09-2021, 08:12 AM
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I thought the focus of this post was the definitive fact that the mRNA used in COVID vaccines does not modify DNA.
It is, along with the fact that mRNA is not new, but a well-tested methodology.

There's been so much misinformation from anti-vaxxers and 'quack' doctors I got interested enough to check.

I've been vaccinated - it's the only way we'll get through this quickly.
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Old 04-09-2021, 08:23 AM
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Originally Posted by Tmarkwald View Post
It is, along with the fact that mRNA is not new, but a well-tested methodology.

There's been so much misinformation from anti-vaxxers and 'quack' doctors I got interested enough to check.

I've been vaccinated - it's the only way we'll get through this quickly.
Just because mRNA has been experimented with for 20 years, does not make it a “well tested methodology”...
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Old 04-09-2021, 08:26 AM
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A little history:
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Old 04-09-2021, 08:31 AM
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Quote:
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A little history:
Nobody can read that - it's way too small
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Old 04-09-2021, 08:39 AM
Tmarkwald Tmarkwald is offline
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Just because mRNA has been experimented with for 20 years, does not make it a “well tested methodology”...
How many years and how many people does it take - initial testing was with 75,000 volunteers, 20 years and thousands more, and now we're at hundreds of millions inoculated.

You do realize that testing with mRNA vaccines started when Reagan was President? And NOBODY has has fatal consequences directly due to the technology?

This has been tested incredibly thoroughly.

Unfortunately, people think it's political rather than scientific or medical. Kinda like we've seen in the past where a medicine cures but because it is praised by someone you don't like, you take the other side purely out of spite.

There are people who believed all the nonsense about mRNA and are now dead, whereas the hundreds of millions who believe the doctors and scientists are out living their lives.

I choose life.

I can't convince the inconvincible. I just hope those who ignore the science don't pay the ultimate price.
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Old 04-09-2021, 08:41 AM
Tmarkwald Tmarkwald is offline
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Has anybody noticed that the only SAFE vaccines are the mRNA Vaccines?

Specifically Pfizer has come out on top, With Moderna have issues, but still available.

J & J has caused numerous issues and is now being pulled in some states;

AstraZeneca will not be imported into the US due to complications.
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Old 04-09-2021, 12:04 PM
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Maybe a little better:
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Old 04-09-2021, 12:35 PM
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Quote:
Originally Posted by Tmarkwald View Post
How many years and how many people does it take - initial testing was with 75,000 volunteers, 20 years and thousands more, and now we're at hundreds of millions inoculated.

You do realize that testing with mRNA vaccines started when Reagan was President? And NOBODY has has fatal consequences directly due to the technology?

This has been tested incredibly thoroughly.

Unfortunately, people think it's political rather than scientific or medical. Kinda like we've seen in the past where a medicine cures but because it is praised by someone you don't like, you take the other side purely out of spite.

There are people who believed all the nonsense about mRNA and are now dead, whereas the hundreds of millions who believe the doctors and scientists are out living their lives.

I choose life.

I can't convince the inconvincible. I just hope those who ignore the science don't pay the ultimate price.
Tmarkwald, thanks for this thread & for doing the research! The links you provided were very helpful, interesting and (to me) believable. Your penultimate comment above is also very true and, unfortunately, to be expected; there are still those who chose to believe that the earth is flat, among other things. Denying vaccine/medical science is just gonna happen...
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Old 04-09-2021, 01:13 PM
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Quote:
Originally Posted by Boffin View Post
I thought the focus of this post was the definitive fact that the mRNA used in COVID vaccines does not modify DNA.
The thread is titled, "The Real Truth About Messenger RNA". The focus is to educate about many aspects of the mRNA technology that folks are leery about. The focus, as far as I understand it is to also debunk the myths perpetuated by those conspiracy theories that try to undermine and scare people half to death about the mRNA technology.

There are enough people in our country who are totally against any vaccines and then add in this new technology that is actually not really "new" and we, as a country, will have a difficult time achieving a herd immunity SAFELY.

Going the way of Dr. Scott Atlas who advocates NATURAL herd immunity, is welcoming many more deaths than can be achieved with immunity from vaccines. It is imperative that those people who are either frightened, or do not trust the government or are just downright anti-vaxxers, need to be educated about these mRNA vaccines.
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Old 04-09-2021, 01:17 PM
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Originally Posted by Swoop View Post
Just because mRNA has been experimented with for 20 years, does not make it a “well tested methodology”...
The RNA from the vaccine is actually eliminated from the body within hours. How can RNA possibly cause any "long term" side effects is what I would like to find out. Does anyone have any information that claims that "long term" effects of the mRNA vaccines are even a remote possibility? Please supply a link if you have that information. Thanks.
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