The real truth about messenger RNA
 

Studies and clinical trials on RNA vaccines for other viruses – and even cancers – have been going on for a decade.

Nobody getting the Moderna or Pfizer vaccine is a test subject of any kind. These are not experimental vaccines in any way. And they do not modify your dna.

Three ways RNA is being used in the next generation of medical treatment

This quote come directly from the link you provided:
“The mRNA vaccines that are used to protect against SARS-CoV-2 (the virus that causes COVID-19) are the first of their kind to be licensed for widespread human use.”

Since 2010, most novel vaccines approved by the FDA required about 8 years of clinical development and were based on evidence from a median of 7 clinical trials, including at least 2 pivotal efficacy trials that were randomized, masked, and used a comparator group. Certainly not the case as it pertains the Covid vaccines...

Yes, then it goes on to say that studies and clinical trials on RNA vaccines for other viruses – and even cancers – have been going on for a decade. And the key word is 'licensed', since they've passed the checks and trials and determined that the vaccine poses no health risk.

So, you have to either accept or reject the scientists who developed these mRna vaccines. Totally up to you.

I'm simply providing a link to the data. How anyone interprets the data is up to them. The point being made is that this technology and method wasn't created overnight - not by a long shot.

Preclinical work on therapeutic mRNA goes back at least to 1990, 20 years ago...

Want to Know More About mRNA Before Your COVID Jab? | MedPage Today

Never Been Done Before?

While an mRNA vaccine has never been on the market anywhere in the world, mRNA vaccines have been tested in humans before, for at least four infectious diseases: rabies, influenza, cytomegalovirus, and Zika.

mRNA can target tumor-associated antigens expressed mainly by cancerous cells, like certain growth factors. These vaccines have been tested in a range of cancers, including acute myeloid leukemia, multiple myeloma, glioblastoma, melanoma, prostate cancer, and others.

Why Did Earlier Vaccines Stall?

"A major factor is that there's not a sense of urgency," Dennis Burton, PhD, of Scripps Translational Research Clinic in La Jolla, California, told MedPage Today.

Zika has been relatively contained; rabies vaccines are already sufficiently effective; and influenza remains a difficult target, Burton said.

...based on the sheer number of people who will be vaccinated for COVID-19, events will occur, and most will likely be unrelated to the vaccine.

"One of the things we're most concerned about is that people won't get vaccinated," he said. "But the risks of this disease are going to be way higher than the risks associated with vaccination."

“Clinical trials for 75,000 people show it’s safe and it’s 95 percent effective,” Dr. Weissman said. “That’s pretty good data to convince people that it is OK.”
While mRNA is a new technology, experts have been working on it for years.

“It’s not just as though these technologies were just starting to be developed during the pandemic,” Dr. Moss said. “There has been a lot of preparatory work.”


This is part of The Associated Press’ ongoing effort to fact-check misinformation that is shared widely online, including work with Facebook to identify and reduce the circulation of false stories on the platform.

Pfizer and Moderna did not skip animal trials

I thought the focus of this post was the definitive fact that the mRNA used in COVID vaccines does not modify DNA.

It is, along with the fact that mRNA is not new, but a well-tested methodology.

There's been so much misinformation from anti-vaxxers and 'quack' doctors I got interested enough to check.

I've been vaccinated - it's the only way we'll get through this quickly.

Just because mRNA has been experimented with for 20 years, does not make it a “well tested methodology”...

A little history:

Nobody can read that - it's way too small

How many years and how many people does it take - initial testing was with 75,000 volunteers, 20 years and thousands more, and now we're at hundreds of millions inoculated.

You do realize that testing with mRNA vaccines started when Reagan was President? And NOBODY has has fatal consequences directly due to the technology?

This has been tested incredibly thoroughly.

Unfortunately, people think it's political rather than scientific or medical. Kinda like we've seen in the past where a medicine cures but because it is praised by someone you don't like, you take the other side purely out of spite.

There are people who believed all the nonsense about mRNA and are now dead, whereas the hundreds of millions who believe the doctors and scientists are out living their lives.

I choose life.

I can't convince the inconvincible. I just hope those who ignore the science don't pay the ultimate price.

Has anybody noticed that the only SAFE vaccines are the mRNA Vaccines?

Specifically Pfizer has come out on top, With Moderna have issues, but still available.

J & J has caused numerous issues and is now being pulled in some states;

AstraZeneca will not be imported into the US due to complications.

Maybe a little better:

Tmarkwald, thanks for this thread & for doing the research! The links you provided were very helpful, interesting and (to me) believable. Your penultimate comment above is also very true and, unfortunately, to be expected; there are still those who chose to believe that the earth is flat, among other things. Denying vaccine/medical science is just gonna happen...

The thread is titled, "The Real Truth About Messenger RNA". The focus is to educate about many aspects of the mRNA technology that folks are leery about. The focus, as far as I understand it is to also debunk the myths perpetuated by those conspiracy theories that try to undermine and scare people half to death about the mRNA technology.

There are enough people in our country who are totally against any vaccines and then add in this new technology that is actually not really "new" and we, as a country, will have a difficult time achieving a herd immunity SAFELY.

Going the way of Dr. Scott Atlas who advocates NATURAL herd immunity, is welcoming many more deaths than can be achieved with immunity from vaccines. It is imperative that those people who are either frightened, or do not trust the government or are just downright anti-vaxxers, need to be educated about these mRNA vaccines.

The RNA from the vaccine is actually eliminated from the body within hours. How can RNA possibly cause any "long term" side effects is what I would like to find out. Does anyone have any information that claims that "long term" effects of the mRNA vaccines are even a remote possibility? Please supply a link if you have that information. Thanks.

This enclosed graphic is too small for me to read. Any chance you can provide a link?

Better. Thank you.

Thank goodness for science and scientists who devote their professional lives for the good of man. Many thanks.

Trusting Big Pharma is like trusting the government

Can’t believe either one of them

I had my 2 vaccines but I truly believe that it's longitudinal studies over 10, 20 or 30 yrs that tell the true story of what vaccines or environmental factors really do to our bodies.

Denying vaccine/medical science is just gonna happen...

Sad, but true.

Just be glad that you aren't one of the 500,000+ that either poo-pooed the vaccine or weren't fortunate enough to have had it available for them to use. I, too, have had my Pfizer series, and with my being 79 years old, I couldn't care less if the vaccine causes me to grow a third eye. At least I'll still be upright and taking nourishment, and not included in the 500,000+.

And that's why we listen to the science, and that's the whole reason for the posts... too many people talk, too few actually research and read the facts.

When I post, I send the links and substantiation for the comments.

How many years would it take to make it well test? We would still be dying from measles, mumps and crippled by polio if we followed your timeline.

Those people were the ones that slept through high school science classes.

Maybe we could have waited the normal 5-8 years to release it. World wide another twenty million people dead, economies destroyed, massive mental health issues, hundreds of thousands if not millions of suicides, and a complete generation of uneducated kids with depression and other socialization issues. Life if full of risks, and sometimes you just have to take one. I think these vaccines are way down the list as far as risks are concerned.

Some people posting here “believe the science.” In fact, the science frequently is inconclusive or directly opposed to other science, much like economists and climate control “geniuses.” You choose to believe you did the right thing by taking inoculations and falsely conclude that people who do not will die or are “wrong” not to take or are antivaxxers. In fact, many people want to consider their options before rolling with the masses. The death number of 2019 and 2020 are about 50,000 different (50,000 more deaths in 2020) not 500,000 different, indicating 500,000 MORE people did NOT DIE OF THE CHINESE VIRUS. The virus has been a useful political, control and money tool and continues to be so since big pharm is now coming out with a booster shot. Get in line.

The statement above ... no matter who is making it ... is what I reject. It is stated as if it is fact but it is not. With a 99.97% chance of NOT DYING from COVID, I personally judge the risk of the shot (not a vaccine) to be higher than just waiting my turn to be exposed to the virus.

The shot (not a vaccine) does not prevent infection; it only (possibly) protects from getting sick after infection. Everyone, everywhere will be exposed / infected at some time, somewhere. I choose to trust my unaltered immune system. And it is my choice.

You get to make your choice about who you believe and trust. Good luck.

Another statement that many people accept as fact but in no way proven. Used only to coerce those who refuse to follow the crowd.

Oh - you mean like how the media and mainstream pooh pooh'd the use of Hydroxychloriquine after the word passed Trump's lips? Proven effective when used VERY early (link Zinc), it was rejected because of a topic we're not allowed to mention in this forum without getting our asses reamed. But, it's true. You could go google now and find all kinds of citations about how HCQ is not effective for COVID early on and that is all the result of Mr. Trump citing the claims of it working by medical professionals that were on the ground treating patients. When have you ever seen a drug that has been around for decades ... is still available ... is declared ineffective for a particular disease (COVID) ... and then banned for that purpose? I mean, aspirin won't cure leukemia but no one is banning its use for that. HCQ was banned (and many people died) so Trump wouldn't look good.

And I'll ask again: Where in the world did you get those numbers? They are wrong!

The data show an increase of approximately 560,000 deaths in 2020. In each of 2017, 2018, and 2019 there were about 2.8M deaths. In 2020 there were 3.4M deaths. That is a difference of 600,000 NOT 50,000!

See the National Center for Healdh Statistics (NCHS) Mortality Surveillance chart at the bottom of this CDC page.

Download the data and do your own math.

Well, let me augment the statement then:

Can't trust Big Pharma or the government or scientists drawing paychecks from either of them.

"I personally judge the risk ...."
AND
"You get to make your choice about who you believe and trust."

I will trust the work of scientists and researchers around the world based on studies and data analysis before I trust someone's personal judgment based on ....what? I was going to say misinformation and fear but you've provided absolutely nothing, not even links to debunked sources, to show what you base your assertions on.

Legal immunity
 

Why did the government feel it was necessary to absolve vaccine companies from legal ramifications?

I agree? And why has 50% of the first responders decided not to be vaccinated. I have had the Covid already, and I have the antibodies in my blood to fight the Covid. I give blood, and they would like for me to give even more.

You are certainly entitled to express your opinions but if you come to a public forum with incorrect numbers you will be called out. Regarding the number of "excess deaths" from the start of the pandemic to now, the number is approximately 500K and reflects the increase in the number of deaths either directly or indirectly from COVID-19. Go to the CDC website and check their data. The number of deaths per year is a remarkably consistent number. "Excess deaths" is the increase in the number of deaths over what would be expected. It isn't impacted by how death is recorded on death certificates.

Excess Deaths Associated with COVID-19

Probably because otherwise the companies would not have released the vaccines before many more years of studies. While we waited those years for the studies, tens of thousands more would have died.

Fact check
 

Fact check by the associated press or any other press seems these days to mean editing and deleting any information they don't want you to have. The word "they" refers to many entities filtering information and free speech. When did all the social media become the decider of what news is made available to the public? I for one am perfectable of deciding for myself what I believe or disbelieve, I don't need the press and social media owners doing that for me.

Because a small number of people will have a bad outcome from taking the vaccine. This is predictable. There would almost certainly be no negligence involved. Everything in life is a risk and there are tradeoffs. You step outside your front door and go for a walk, because exercise will improve your health, and you could be killed by a car. There are also risks associated with the coronavirus and the vaccine. If you are young and healthy, the probability of a bad outcome from being infected is very small. If you are over 65 with several health issues, the probability of a bad outcome from the coronavirus is much higher. The vaccines reduce your probability of serious disease and death to essentially zero. In exchange for this remarkable effectiveness, you accept that there is also a very small probability of the vaccine itself causing an issue. You, as well as everyone else, can make an informed decision. However, if you are a healthy person you need to ask yourself the following question: is the probability of a bad outcome from becoming infected higher than the probability of a bad outcome from taking the vaccine?

I'm a conservative, but you are drinking WAY too much of the kool-aid

Oh, oh. So glad we have so many experts at the Villages.