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-   -   Interesting Research CRISPR (https://www.talkofthevillages.com/forums/current-events-news-541/interesting-research-crispr-342582/)

Boffin 07-10-2023 12:33 PM

Interesting Research CRISPR
 
Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas9 genome editing technology. In the field of genome engineering, the term “CRISPR” or “CRISPR-Cas9” is often used loosely to refer to the various CRISPR-Cas9 and -CPF1, (and other) systems that can be programmed to target specific stretches of genetic code and to edit DNA at precise locations, as well as for other purposes, such as for new diagnostic tools. With these systems, researchers can permanently modify genes in living cells and organisms and, in the future, may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease.

Two Bills 07-10-2023 12:51 PM

I like CRISPR fries as well.

Stu from NYC 07-10-2023 02:12 PM

Quote:

Originally Posted by Boffin (Post 2233846)
Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas9 genome editing technology. In the field of genome engineering, the term “CRISPR” or “CRISPR-Cas9” is often used loosely to refer to the various CRISPR-Cas9 and -CPF1, (and other) systems that can be programmed to target specific stretches of genetic code and to edit DNA at precise locations, as well as for other purposes, such as for new diagnostic tools. With these systems, researchers can permanently modify genes in living cells and organisms and, in the future, may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease.

If I understood this would probably agree.

Two Bills 07-10-2023 02:36 PM

Quote:

Originally Posted by Stu from NYC (Post 2233880)
If I understood this would probably agree.

Need to be a member of Mensa these days on TOTV!
Haven't a clue what post was about.

Stu from NYC 07-10-2023 03:42 PM

Quote:

Originally Posted by Two Bills (Post 2233883)
Need to be a member of Mensa these days on TOTV!
Haven't a clue what post was about.

Apparently something to do with modifying bacteria.

Keefelane66 07-10-2023 03:51 PM

This could get into similar MRNA as did with COVID. Some will look at it objectively others will assume it’s bad. Science can’t live with it or without it.

Keefelane66 07-10-2023 03:56 PM

Quote:

Originally Posted by Two Bills (Post 2233883)
Need to be a member of Mensa these days on TOTV!
Haven't a clue what post was about.

In simple English but not really

“ CRISPR (short for “clustered regularly interspaced short palindromic repeats”) is a technology that research scientists use to selectively modify the DNA of living organisms. CRISPR was adapted for use in the laboratory from naturally occurring genome editing systems found in bacteria.Jul 1, 2023”

Boffin 07-10-2023 05:08 PM

Treatment of diseases
 
For example:

Cancer
Blood disorders
Blindness
AIDS
Cystic fibrosis
Muscular dystrophy
Huntington's disease
COVID-19

HoosierPa 07-11-2023 04:42 AM

Quote:

Originally Posted by Boffin (Post 2233846)
Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas9 genome editing technology. In the field of genome engineering, the term “CRISPR” or “CRISPR-Cas9” is often used loosely to refer to the various CRISPR-Cas9 and -CPF1, (and other) systems that can be programmed to target specific stretches of genetic code and to edit DNA at precise locations, as well as for other purposes, such as for new diagnostic tools. With these systems, researchers can permanently modify genes in living cells and organisms and, in the future, may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease.

I had a bacterial infection once. Is that the same thing ?

GizmoWhiskers 07-11-2023 04:46 AM

Interesting word salads pop up on ToTV to generate ad revenue I suppose.

ToTV infractraction clickbait but... ICMEC reports about 8 MILLION!! children go "missing" a year. How about T V focuses on making sure local and visitor kids stay safe. How about the world focuses on ending kids from "missing" for a while rather than bacteria?

WingedFoot78 07-11-2023 05:17 AM

Ditto!

Kerlampert 07-11-2023 05:31 AM

This may prove to be one of the most important breakthroughs in identifying and treating many genetically based diseases. Of all times!

kendi 07-11-2023 06:29 AM

Quote:

Originally Posted by Keefelane66 (Post 2233902)
This could get into similar MRNA as did with COVID. Some will look at it objectively others will assume it’s bad. Science can’t live with it or without it.

That’s because Most anything can be used for the good of others or for self centered reasons which ultimately end up hurting others. So most if not all scientific advancements will be used for both. That is unfortunately the human condition.

PersonOfInterest 07-11-2023 06:44 AM

Do I need a new one already?

The Chipster 07-11-2023 07:01 AM

Get educated, for your grandkids' sake
 
I had heard about CRISPR for the past few years, but did not understand it. Then I recently read "CODE BREAKER" by Walter Isaacson, which is centered around the female DNA scientist who invented the CRISPR process. An amazing book that, while technical in parts, will give you a glimpse of the future of medicine. For real - NO POLITICS.

jmpalladino 07-11-2023 07:16 AM

Wth
 
Quote:

Originally Posted by Boffin (Post 2233846)
Clustered Regularly Interspaced Short Palindromic Repeats, which are the hallmark of a bacterial defense system that forms the basis for CRISPR-Cas9 genome editing technology. In the field of genome engineering, the term “CRISPR” or “CRISPR-Cas9” is often used loosely to refer to the various CRISPR-Cas9 and -CPF1, (and other) systems that can be programmed to target specific stretches of genetic code and to edit DNA at precise locations, as well as for other purposes, such as for new diagnostic tools. With these systems, researchers can permanently modify genes in living cells and organisms and, in the future, may make it possible to correct mutations at precise locations in the human genome in order to treat genetic causes of disease.

WTF- I was always taught if you can't say something that your audience can understand, then you are not as bright as you think you are!

Bridget Staunton 07-11-2023 07:19 AM

Your post not necessary, telling people about latest technology is wonderful

mntlblok 07-11-2023 07:26 AM

Crisper just hurts my ear
 
Quote:

Originally Posted by Two Bills (Post 2233859)
I like CRISPR fries as well.

Crispier vs Crisper - What's the difference? | WikiDiff


Crispier vs Crisper - What's the difference?
crispier | crisper |


As adjectives the difference between crispier and crisper is that crispier is comparative of crispy while crisper is comparative of crisp.

As a noun crisper is a cooled food storage container, used to cool items that do not require complete refrigeration.

Two Bills 07-11-2023 07:31 AM

Quote:

Originally Posted by mntlblok (Post 2234059)
Crispier vs Crisper - What's the difference? | WikiDiff


Crispier vs Crisper - What's the difference?
crispier | crisper |


As adjectives the difference between crispier and crisperis that crispier is comparative of crispy while crisper is comparative of crisp.

As a noun crisper is a cooled food storage container, used to cool items that do not require complete refrigeration.

.......and Crisps in UK are Chips in US.

mntlblok 07-11-2023 07:35 AM

Codons and Gamow
 
Quote:

Originally Posted by Two Bills (Post 2233883)
Need to be a member of Mensa these days on TOTV!
Haven't a clue what post was about.

"Codons" would be a simple and enlightening place to start. That nature came up with this system blows my mind.

A side trip through Gamow would be fun, including Alpher, Bethe, Gamow. :-)

Genetic code - Wikipedia

hypart 07-11-2023 08:06 AM

There's a great documentary on this subject called Human Nature. I highly suggest it. It was one of my favorite films of 2020.

I saw it on Netflix back then but currently only available for rental on Amazon Prime video for $3.99

mntlblok 07-11-2023 08:16 AM

Quote:

Originally Posted by Two Bills (Post 2234062)
.......and Crisps in UK are Chips in US.

And wherever that Geicko gecko is from. :-)

rockyhyder 07-11-2023 08:21 AM

Good and Bad
 
Quote:

Originally Posted by The Chipster (Post 2234039)
I had heard about CRISPR for the past few years, but did not understand it. Then I recently read "CODE BREAKER" by Walter Isaacson, which is centered around the female DNA scientist who invented the CRISPR process. An amazing book that, while technical in parts, will give you a glimpse of the future of medicine. For real - NO POLITICS.

While the medical treatment impacts can be marvelous the other side of the coin is very concerning (biological warfare). This technology in the hands of the CCP could make COVID look like a walk in the park. As mentioned earlier, scientific advancement has historically been used for both good and bad (see Alfred Noble). I’m pulling for the good wolf but always aware of the bad wolf’s presence.

Stu from NYC 07-11-2023 08:58 AM

I will ask my 12 year old grandson about this and ask him what he thinks.


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