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-   -   Hydroxychloroquine (https://www.talkofthevillages.com/forums/medical-health-discussion-94/hydroxychloroquine-304614/)

skyking 03-30-2020 11:24 AM

Hydroxychloroquine
 
At least one hospital is administering this as a prophylaxis to medical professionals giving care to COVID-19 patients.

(link for blueash)

New Jersey doctor gives update on use of hydroxychloroquine, remdesivir on coronavirus patients

New Jersey doctor gives update on use of hydroxychloroquine, remdesivir on coronavirus patients | Fox News

blueash 03-30-2020 11:38 AM

Careful reading please, but thank you for a link. The Foxnews story says
Quote:

the other trial that we are looking at right now that we hope to get launched later this week, we’ve actually had it fast-tracked up until now, is actually using hydroxychloroquine for what we call chemoprophylaxis or prevention for front-line caregivers,” he added.
Note that it doesn't say they are doing it, rather that they hope to launch. And it doesn't say medical professionals, it says front-line caregivers. That is not a minor quibble as the previous sentence in the story is about spread in nursing homes. So it might mean giving it to care givers in nursing homes.

I am all in favor of people doing studies. And I am encouraged by the word "trial" in his comment. It suggests something more vigorous than just giving everyone hydroxychloroquine. Hopefully they are going to collect data but I understand that can be a secondary issue. As I have written in other threads I hope this works, bigly.

bumpygreens 03-30-2020 11:49 AM

It will be interesting to see if this works. The drug is believed to prevent the entry of the virus into the endosome where it produces single stranded RNA to replicate itself. If it works, the virus wouldn't be able to spread.

GoodLife 03-30-2020 12:19 PM

Quote:

Originally Posted by blueash (Post 1736811)
Careful reading please, but thank you for a link. The Foxnews story says


Note that it doesn't say they are doing it, rather that they hope to launch. And it doesn't say medical professionals, it says front-line caregivers. That is not a minor quibble as the previous sentence in the story is about spread in nursing homes. So it might mean giving it to care givers in nursing homes.

I am all in favor of people doing studies. And I am encouraged by the word "trial" in his comment. It suggests something more vigorous than just giving everyone hydroxychloroquine. Hopefully they are going to collect data but I understand that can be a secondary issue. As I have written in other threads I hope this works, bigly.

Lots of Doctors are "doing it" right now and also taking the drug as a prophylactic themselves.

https://www.washingtonpost.com/busin...rus-treatment/

skyking 03-30-2020 12:23 PM

Quote:

Originally Posted by GoodLife (Post 1736830)
Lots of Doctors are "doing it" right now and also taking the drug as a prophylactic themselves.

https://www.washingtonpost.com/busin...rus-treatment/

Yes they are. Others are waiting for efficacy studies while patients die. Choose your doctors wisely.

GoodLife 03-30-2020 12:39 PM

Quote:

Originally Posted by skyking (Post 1736835)
Yes they are. Others are waiting for efficacy studies while patients die. Choose your doctors wisely.

Here are two youtube videos by Doctors explaining how it works, 2nd one is more technical.

COVID-19 Update 8: Zinc and chloroquine for the treatment of COVID-19? - YouTube

Coronavirus Epidemic Update 34: US Cases Surge, Chloroquine & Zinc Treatment Combo, Italy Lockdown - YouTube

skyking 03-30-2020 12:57 PM

Quote:

Originally Posted by blueash (Post 1736811)
Careful reading please, but thank you for a link. The Foxnews story says


Note that it doesn't say they are doing it, rather that they hope to launch. And it doesn't say medical professionals, it says front-line caregivers. That is not a minor quibble as the previous sentence in the story is about spread in nursing homes. So it might mean giving it to care givers in nursing homes. (And I think caregivers in nursing homes are healthcare professionals.)

I am all in favor of people doing studies. And I am encouraged by the word "trial" in his comment. It suggests something more vigorous than just giving everyone hydroxychloroquine. Hopefully they are going to collect data but I understand that can be a secondary issue. As I have written in other threads I hope this works, bigly.

I think the doctors, nurses, respiratory techs, etc. who are treating these patients would be considered "front line" especially if they are in the ER or some form of triage.

skyking 03-30-2020 04:16 PM

FDA Gives Emergency Authorization On Use Of Malaria Drug For COVID-19 Care | iHeartRadio

Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[5] In 2017, it was the 128th-most-prescribed medication in the United States, with more than five million prescriptions.
__________________________________________________ _______________________________

World Health Organization (2019). World Health Organization model list of essential medicines: 21st list. Geneva: World Health Organization. hdl:10665/325771.
WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO

BarbC2016 03-31-2020 08:33 AM

Interesting article on what Italy is doing...
 
Italy Finally Starts Mass Treatment with Hydroxychloroquine

The Italian doctors are noting that the drug is best used in the early stages of the infection.

graciegirl 03-31-2020 09:02 AM

Blueash. You and I may not agree sometimes about certain issues but I respect your medical training and your scientific reticence and your amazing mind. Thank God for our medical professionals, particularly M.D.s. That goes for you too Golfing Eagle and my neighbor, you know who you are. Sometimes being gifted is extremely hard.

Dr Winston O Boogie jr 03-31-2020 09:07 AM

Quote:

Originally Posted by skyking (Post 1736954)
FDA Gives Emergency Authorization On Use Of Malaria Drug For COVID-19 Care | iHeartRadio

Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[5] In 2017, it was the 128th-most-prescribed medication in the United States, with more than five million prescriptions.
__________________________________________________ _______________________________

World Health Organization (2019). World Health Organization model list of essential medicines: 21st list. Geneva: World Health Organization. hdl:10665/325771.
WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO

The problem is that hydroxychloraquine has not been used in conjunction with other drugs such as z-packs and azithromyacin which is being done to treat Covid-19 patients. Not enough is known about the interaction of these medications.

I believe that it should be up to the patient and doctor to decide whether or not to take this risk. It seems small to me, but for someone that is young and healthy and is experiencing mild symptoms, the risk may not be worth it.

If I, on the other hand, contract this virus, I will be screaming for these drugs. But then again, I'm 68 years old with several underlying conditions that put me at great risk.

blueash 03-31-2020 11:02 AM

Quote:

Originally Posted by BarbC2016 (Post 1737222)
Italy Finally Starts Mass Treatment with Hydroxychloroquine

The Italian doctors are noting that the drug is best used in the early stages of the infection.

Please critically evaluate these statements from the article you linked [thank you for a link]

Quote:

We have just understood that the virus has an evolution in two phases and that it is during the second phase, after a few days (about a week), that the situation can suddenly, in 24 or 48 hours, worsen and leads to respiratory failure requiring intensive care.
The results that we are starting to accumulate suggest that hydroxychloroquine administered early, gives the possibility of avoiding this evolution in a majority of patients and is also helping us to prevent hospitals from filling up.
Now seeing as approximately 80 % of patients with early Covid never progress why would a finding that the majority of patients given a treatment don't progress be meaningful? If only 20% of early patients given the medicine progressed would you be impressed? Of course not as the known pattern of Covid is that 80% of patients given only symptomatic treatment don't progress to being sick enough to fill up hospitals.

rmd2 03-31-2020 11:17 AM

Hydroxychloroquine
 
Quote:

Originally Posted by skyking (Post 1736954)
FDA Gives Emergency Authorization On Use Of Malaria Drug For COVID-19 Care | iHeartRadio

Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[5] In 2017, it was the 128th-most-prescribed medication in the United States, with more than five million prescriptions.
__________________________________________________ _______________________________

World Health Organization (2019). World Health Organization model list of essential medicines: 21st list. Geneva: World Health Organization. hdl:10665/325771.
WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO


Not only effective and safe but also shortens the "viral shedding" time so that promotes less transmission. I would absolutely use this drug.

TandHSTAR@AOL.com 03-31-2020 02:33 PM

Thank you for a voice of reason. People hear what they want to hear. That's how rumors start and false hope instilled in people. Everyone read all the fine print not just the part you want to hear. There is a difference between doctor and scientists. Between experimental and known results. Please stop. Too.many people believe what you pass on.


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