From what I understand, and please correct me if this is wrong, the only difference between the Pfizer and Moderna vaccines is in the inert ingredients. It's a bit like the difference between Tylenol and a generic brand. The actual medication is identical but the binders and fillers are different.
The Johnson and Johnson one shot vaccine is somewhere between 66% and 72% effective versus the 95% for the Pfizer and Moderna vaccines.
I don't think that any vaccine has ever been 100% effective. The annual influenza vaccine reduces the risk of flu illness by between 40% and 60%.
Even birth control pill fail .3% of the time.
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