New Melanoma Drug

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Old 08-18-2011, 12:47 PM
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Avista Avista is offline
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Default New Melanoma Drug

This is interesting:
The U.S. Food and Drug Administration approved a first-of-its kind drug for the treatment of certain types of melanoma.

The Moffitt Cancer Center was the only institution in Florida that conducted a trial for the drug, vemurafenib, a company statement said.

The drug, which has the brand name Zelboraf, was approved for treating metastic melanoma patients who test positive for a gene mutation called BRAFV600E. The mutant BRAF protein is found in about half of all cases of melanoma, the most lethal form of skin cancer, the statement said.

Dr. Jeffrey Weber, director of the Donald A. Adam Comprehensive Melanoma Research Center at Moffitt, was an investigator on a Phase II student that enrolled 132 patients. The study showed that vemurafenib (pronounced vem-yoo-RAF-en-ib) shrank tumors in 52 percent of trial participants, and participants lived a media of 6.2 percent months without their disease getting worse, the statement said.

The drug is manufactured by Genentech, a member of the Roche Group (OTCQX: RHHBY). It’s expected to be available in the U.S. within two weeks of approval and will be distributed through specialty mail-order pharmacies, Genentech said.
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Old 08-18-2011, 04:21 PM
LivingLarge LivingLarge is offline
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Nice to see Moffitt associated with this. Makes me proud that TV has a Moffitt connection.
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Old 08-18-2011, 06:56 PM
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asianthree asianthree is offline
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Unless someone got it wrong on the news the cost per month is $9,000. heard the same thing on different channel again..pretty sure we all will be waiting for a generic at that cost
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Old 08-23-2011, 09:08 PM
whartonjelly whartonjelly is offline
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It is more like 30000 a dose. My daughters father in law, used it, and he lived about 2 months after his melenoma diagnosis. He is being buried tomorrow. He was lucky to have Insurance. He had turned 66. He had a lesion removed from his back 2 years ago. It came back with a vengence, invading his brain,lungs, bones. Luckily his brain did not interpret any pain. He died less than 48 hours after he was put on hospice, and had signed his DNR. He was the second person to use it at the University Hospital in Ciny. I do not believe it worked at all for him.
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